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KMID : 1138720070330010039
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Korean Public Health Research
2007 Volume.33 No. 1 p.39 ~ p.46
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Association between Metabolic Syndrome and Chronic Kidney Disease
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Eun Jin-Seok
Lee Yong-Hwan
Lee Myeong-Sook
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Abstract
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The aim of this study was to evaluate the association between the metabolic syndrome and risk for chronic kidney disease in a sample of Korean adults. A total of 1,421 health screen examinees above 40 years old who were examined in a hospital in Busan November 2004 to February 2006 were enrolled in this study. The height, weight, waist circumference, and systolic and diastolic blood pressure of the subjects were examined and fasting blood glucose, HDL cholesterol, triglyceride, and creatinine were measured by sampling in venous blood. Chronic kidney disease was defined as a glomerular filtration rate less than 60 mL/min per 1.73 m2. After adjusting for age, sex, body mass index, smoking and drinking, abdominal obesity and hypertension were significantly associated with an increased odds ratio for chronic kidney disease of 1.87 (95% CI, 1.07 to 3.43) and 1.86 (95% CI, 1.03 to 3.35), respectively. Compared with subjects with 0 or 1 component of the metabolic syndrome, subjects with 4 or 5 components of the metabolic syndrome had odds ratio of chronic kidney disease of 3.12 (95% CI, 1.25 to 7.81). These results suggest that subjects with more components of the metabolic syndrome had an increased risk for developing chronic kidney disease. Of the components of the metabolic syndrome, hypertension and abdominal obesity were most associated with chronic kidney disease.
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KEYWORD
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metabolic syndrome, chronic kidney disease, hypertension, abdominal obesity
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